In collaboration with an expert partner laboratory, Lawson Scientific is able to offer Dynamic Vapour Sorption (DVS) analysis using the DVS Advantage by Surface Measurement Systems Ltd. As experts in method development and validation for the pharmaceutical industry with many years industrial experience working with hundreds of API’s, we can offer a real specialist service in this arena.

The DVS Advantage uses dry air or dry nitrogen as carrier gas. The user can select one of any two vapor sources, originating from liquid organic solvents or water held at the same temperature as the DVS. When the dry carrier gas passes through a solvent, it becomes saturated with the vapours of that solvent. Precise control of the ratio of saturated and dry gas flow is enabled with mass flow control combined with the use of unique real time vapour concentration monitoring. A known concentration of the selected vapour then flows over a sample suspended from a recording ultra-microbalance, which measures the change in weight caused by sorption or desorption of the vapour molecules. These dynamic flow conditions enable the adsorption/desorption processes to be rapidly studied.

This technique is useful for a number of applications over a range of sectors, some examples of which are as follows;

  • Moisture uptake behavior of food and natural materials
  • Stability and caking of food ingredients
  • Moisture diffusion into blister packaging systems
  • Moisture sorption of hydrophobic pharmaceutical materials
  • Surface energies and surface areas of powders using organic vapor probes

    Get in touch for a quote or to find out more about how we can support you ….